Oral solutions are commonly supplied as 10 g/15 mL or similar concentrations; verify the product label.
Prescription classification
Both Rx and OTC strengths exist (verified)
Approved routes of administration
Oral
Applies to
IN; product status and availability may vary by jurisdiction
Approved indications
An osmotic laxative used to treat constipation and, at higher doses, hepatic encephalopathy by reducing ammonia absorption in the gut.
Contraindications (do not use if…)
Avoid in people with galactosaemia or obstruction of the bowel. Use with caution in people with lactose intolerance ‚ check the product formulation.
Important precautions
Adequate fluid intake is important during treatment. If used for hepatic encephalopathy, dosing and monitoring require specialist guidance. Prolonged or excessive use can cause electrolyte imbalance.
Common side effects
Common effects include bloating, flatulence, stomach cramps, and diarrhoea ‚ especially at higher doses or when starting treatment.
Serious side effects — seek urgent medical care
Seek medical attention for severe diarrhoea, signs of dehydration (extreme thirst, reduced urine output), or significant electrolyte disturbance.
Important interactions
Non-absorbable antacids may reduce lactulose's effectiveness. Discuss all medicines and supplements with your pharmacist.
Allergy considerations
Report any known allergy to lactulose or related compounds. Check inactive ingredients if you have other food or medicine allergies.
Pregnancy and lactation
Pregnancy safety
Use with caution — see notes
Notes
Lactulose is generally considered suitable for use in pregnancy for constipation. Confirm with your doctor before starting.
Information
Lactation safety
Use with caution — see notes
Notes
Considered compatible with breastfeeding. Minimal systemic absorption makes it unlikely to affect the infant. Confirm with your doctor if you have concerns.
Children and older adults
Doses are adjusted by age. Use in young children requires a doctor's guidance ‚ do not estimate the dose from adult instructions.
Storage
Store at room temperature in the original container, away from heat and direct sunlight. Keep out of children's reach.
Missed dose
Lactulose is usually taken regularly. If you miss a dose, take it when you remember unless it is close to the next dose. Do not double up.
Overdose
Large accidental doses can cause severe diarrhoea and dehydration. Contact a poison helpline or your doctor if this happens.
If you suspect an overdose or accidental poisoning:
contact your local emergency services or the nearest hospital emergency department immediately. Do not wait for symptoms.
Oral solutions are commonly supplied as 10 g/15 mL or similar concentrations; verify the product label.
Prescription classification
Both Rx and OTC strengths exist (verified)
Approved routes of administration
Oral
Applies to
IN; product status and availability may vary by jurisdiction
Approved indications
An osmotic laxative used to treat constipation and, at higher doses, hepatic encephalopathy by reducing ammonia absorption in the gut.
Contraindications (do not use if…)
Avoid in people with galactosaemia or obstruction of the bowel. Use with caution in people with lactose intolerance ‚ check the product formulation.
Important precautions
Adequate fluid intake is important during treatment. If used for hepatic encephalopathy, dosing and monitoring require specialist guidance. Prolonged or excessive use can cause electrolyte imbalance.
Common side effects
Common effects include bloating, flatulence, stomach cramps, and diarrhoea ‚ especially at higher doses or when starting treatment.
Serious side effects — seek urgent medical care
Seek medical attention for severe diarrhoea, signs of dehydration (extreme thirst, reduced urine output), or significant electrolyte disturbance.
Important interactions
Non-absorbable antacids may reduce lactulose's effectiveness. Discuss all medicines and supplements with your pharmacist.
Allergy considerations
Report any known allergy to lactulose or related compounds. Check inactive ingredients if you have other food or medicine allergies.
Pregnancy and lactation
Pregnancy safety
Use with caution — see notes
Notes
Lactulose is generally considered suitable for use in pregnancy for constipation. Confirm with your doctor before starting.
Information
Lactation safety
Use with caution — see notes
Notes
Considered compatible with breastfeeding. Minimal systemic absorption makes it unlikely to affect the infant. Confirm with your doctor if you have concerns.
Children and older adults
Doses are adjusted by age. Use in young children requires a doctor's guidance ‚ do not estimate the dose from adult instructions.
Storage
Store at room temperature in the original container, away from heat and direct sunlight. Keep out of children's reach.
Missed dose
Lactulose is usually taken regularly. If you miss a dose, take it when you remember unless it is close to the next dose. Do not double up.
Overdose
Large accidental doses can cause severe diarrhoea and dehydration. Contact a poison helpline or your doctor if this happens.
If you suspect an overdose or accidental poisoning:
contact your local emergency services or the nearest hospital emergency department immediately. Do not wait for symptoms.
