Domstal; Motilium (brand availability varies by market)
Dosage form
Tablet
Strength
10 mg tablets; availability and approved uses vary by jurisdiction.
Prescription classification
Prescription only (Schedule H / verified)
Approved routes of administration
Oral
Applies to
IN; product status and availability may vary by jurisdiction
Approved indications
Domperidone acts on gut movement and may be used for selected nausea or vomiting indications where locally approved. It is not suitable for every digestive complaint.
Contraindications (do not use if…)
Do not use domperidone if you have certain heart rhythm conditions, significant electrolyte imbalances, moderate or severe liver problems, or if you take medicines that strongly inhibit CYP3A4 or prolong QT. Check local labelling.
Important precautions
Domperidone may raise the risk of serious heart rhythm problems, particularly at higher doses, with longer use, in older adults, or when taken with interacting medicines. Use it only when specifically recommended by a clinician and follow local restrictions strictly.
Common side effects
Common effects may include dry mouth, headache, and stomach discomfort. Hormonal effects such as breast tenderness or unexpected milk discharge may also occur.
Serious side effects — seek urgent medical care
Seek urgent help for palpitations, fainting, severe dizziness, seizure, or a serious allergic reaction.
Important interactions
Avoid combining domperidone with certain macrolide antibiotics, azole antifungals, or other medicines that prolong QT or strongly inhibit CYP3A4. A full interaction check is essential before use.
Allergy considerations
Do not take domperidone if you have had a serious reaction to it or any product ingredient.
Pregnancy and lactation
Pregnancy safety
Use with caution — see notes
Notes
Use domperidone in pregnancy only if a clinician determines it is necessary and consistent with current local guidance.
Information
Lactation safety
Use with caution — see notes
Notes
Do not use domperidone to increase milk supply without specialist advice — cardiac risks and local recommendations must be considered.
Children and older adults
Use is restricted in some age groups and body weights. Follow current product labelling and seek specialist advice where needed.
Storage
Store in original packaging away from moisture and excess heat, out of children's reach.
Missed dose
Follow the exact prescription instructions. Do not take a double dose — if unsure, ask your pharmacist.
Overdose
Overdose can cause abnormal movements, drowsiness, seizures, or heart rhythm problems. Seek urgent medical attention.
If you suspect an overdose or accidental poisoning:
contact your local emergency services or the nearest hospital emergency department immediately. Do not wait for symptoms.
Domstal; Motilium (brand availability varies by market)
Dosage form
Tablet
Strength
10 mg tablets; availability and approved uses vary by jurisdiction.
Prescription classification
Prescription only (Schedule H / verified)
Approved routes of administration
Oral
Applies to
IN; product status and availability may vary by jurisdiction
Approved indications
Domperidone acts on gut movement and may be used for selected nausea or vomiting indications where locally approved. It is not suitable for every digestive complaint.
Contraindications (do not use if…)
Do not use domperidone if you have certain heart rhythm conditions, significant electrolyte imbalances, moderate or severe liver problems, or if you take medicines that strongly inhibit CYP3A4 or prolong QT. Check local labelling.
Important precautions
Domperidone may raise the risk of serious heart rhythm problems, particularly at higher doses, with longer use, in older adults, or when taken with interacting medicines. Use it only when specifically recommended by a clinician and follow local restrictions strictly.
Common side effects
Common effects may include dry mouth, headache, and stomach discomfort. Hormonal effects such as breast tenderness or unexpected milk discharge may also occur.
Serious side effects — seek urgent medical care
Seek urgent help for palpitations, fainting, severe dizziness, seizure, or a serious allergic reaction.
Important interactions
Avoid combining domperidone with certain macrolide antibiotics, azole antifungals, or other medicines that prolong QT or strongly inhibit CYP3A4. A full interaction check is essential before use.
Allergy considerations
Do not take domperidone if you have had a serious reaction to it or any product ingredient.
Pregnancy and lactation
Pregnancy safety
Use with caution — see notes
Notes
Use domperidone in pregnancy only if a clinician determines it is necessary and consistent with current local guidance.
Information
Lactation safety
Use with caution — see notes
Notes
Do not use domperidone to increase milk supply without specialist advice — cardiac risks and local recommendations must be considered.
Children and older adults
Use is restricted in some age groups and body weights. Follow current product labelling and seek specialist advice where needed.
Storage
Store in original packaging away from moisture and excess heat, out of children's reach.
Missed dose
Follow the exact prescription instructions. Do not take a double dose — if unsure, ask your pharmacist.
Overdose
Overdose can cause abnormal movements, drowsiness, seizures, or heart rhythm problems. Seek urgent medical attention.
If you suspect an overdose or accidental poisoning:
contact your local emergency services or the nearest hospital emergency department immediately. Do not wait for symptoms.
