Emeset; Zofran (brand availability varies by market)
Dosage form
Tablet
Strength
4 mg, 8 mg tablets; orally disintegrating and injectable forms vary.
Prescription classification
Prescription only (Schedule H / verified)
Applies to
IN; product status and availability may vary by jurisdiction
Approved indications
Ondansetron is an antiemetic used to prevent or treat nausea and vomiting in selected clinical settings. Whether it is appropriate depends on the cause of symptoms and the overall clinical picture.
Contraindications (do not use if…)
Do not use ondansetron together with apomorphine. Avoid it if you have had a serious allergic reaction to ondansetron or a related 5-HT3 antagonist. Review cardiac warnings on the product label.
Important precautions
Ondansetron can affect heart rhythm, particularly if you have long-QT syndrome, electrolyte problems, heart disease, or are taking interacting medicines. It can also mask symptoms of serious abdominal conditions.
Common side effects
Common side effects include headache, constipation, dizziness, and tiredness.
Serious side effects — seek urgent medical care
Seek urgent help for fainting, a fast or irregular heartbeat, a severe allergic reaction, severe constipation with abdominal swelling, or symptoms of serotonin syndrome.
Important interactions
Review use with apomorphine, QT-prolonging medicines, serotonergic medicines, and other drugs affecting electrolytes or heart rhythm.
Allergy considerations
Avoid ondansetron if you have had a serious allergic reaction to it or a related medicine. Check product ingredients for other potential allergens.
Pregnancy and lactation
Pregnancy safety
Use with caution — see notes
Notes
A clinician should decide whether ondansetron is right during pregnancy, taking into account the reason for nausea, the timing, and other available options.
Information
Lactation safety
Use with caution — see notes
Notes
Suitability during breastfeeding depends on your specific situation and infant factors. Ask your doctor or pharmacist for individual advice.
Children and older adults
Paediatric use depends on the indication, age, weight, and formulation. Only use a clinician-directed regimen.
Storage
Store in original packaging as directed on the product label. Keep away from excess heat and moisture.
Missed dose
Use only as prescribed or directed on the label. Do not take an extra dose without checking the instructions first.
Overdose
Suspected overdose needs prompt medical advice, especially if fainting, unusual movements, or heart rhythm symptoms occur.
If you suspect an overdose or accidental poisoning:
contact your local emergency services or the nearest hospital emergency department immediately. Do not wait for symptoms.
Emeset; Zofran (brand availability varies by market)
Dosage form
Tablet
Strength
4 mg, 8 mg tablets; orally disintegrating and injectable forms vary.
Prescription classification
Prescription only (Schedule H / verified)
Applies to
IN; product status and availability may vary by jurisdiction
Approved indications
Ondansetron is an antiemetic used to prevent or treat nausea and vomiting in selected clinical settings. Whether it is appropriate depends on the cause of symptoms and the overall clinical picture.
Contraindications (do not use if…)
Do not use ondansetron together with apomorphine. Avoid it if you have had a serious allergic reaction to ondansetron or a related 5-HT3 antagonist. Review cardiac warnings on the product label.
Important precautions
Ondansetron can affect heart rhythm, particularly if you have long-QT syndrome, electrolyte problems, heart disease, or are taking interacting medicines. It can also mask symptoms of serious abdominal conditions.
Common side effects
Common side effects include headache, constipation, dizziness, and tiredness.
Serious side effects — seek urgent medical care
Seek urgent help for fainting, a fast or irregular heartbeat, a severe allergic reaction, severe constipation with abdominal swelling, or symptoms of serotonin syndrome.
Important interactions
Review use with apomorphine, QT-prolonging medicines, serotonergic medicines, and other drugs affecting electrolytes or heart rhythm.
Allergy considerations
Avoid ondansetron if you have had a serious allergic reaction to it or a related medicine. Check product ingredients for other potential allergens.
Pregnancy and lactation
Pregnancy safety
Use with caution — see notes
Notes
A clinician should decide whether ondansetron is right during pregnancy, taking into account the reason for nausea, the timing, and other available options.
Information
Lactation safety
Use with caution — see notes
Notes
Suitability during breastfeeding depends on your specific situation and infant factors. Ask your doctor or pharmacist for individual advice.
Children and older adults
Paediatric use depends on the indication, age, weight, and formulation. Only use a clinician-directed regimen.
Storage
Store in original packaging as directed on the product label. Keep away from excess heat and moisture.
Missed dose
Use only as prescribed or directed on the label. Do not take an extra dose without checking the instructions first.
Overdose
Suspected overdose needs prompt medical advice, especially if fainting, unusual movements, or heart rhythm symptoms occur.
If you suspect an overdose or accidental poisoning:
contact your local emergency services or the nearest hospital emergency department immediately. Do not wait for symptoms.
