Glimepiride

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    About this medicine

    Generic name Glimepiride
    Active ingredients Glimepiride
    Brand names (as verified) Amaryl; Glimy (brand availability varies by market)
    Dosage form Tablet
    Strength 1 mg, 2 mg, 4 mg tablets; dose decided by the prescriber.
    Prescription classification Prescription only (Schedule H / verified)
    Approved routes of administration Oral
    Applies to IN; product status and availability may vary by jurisdiction

    Approved indications

    • Glimepiride is a sulfonylurea used alongside diet and physical activity to improve blood sugar control in selected adults with type 2 diabetes. It is not used for type 1 diabetes or diabetic ketoacidosis.

    Contraindications (do not use if…)

    • Do not use glimepiride for type 1 diabetes or diabetic ketoacidosis. Avoid it if you have had a serious allergic reaction to glimepiride or any product ingredient.

    Important precautions

    • Glimepiride can cause low blood sugar (hypoglycaemia), particularly if you skip meals, drink alcohol, or use other glucose-lowering medicines. Monitor blood glucose as advised and inform your care team about kidney or liver disease.

    Common side effects

    • Common side effects include low blood sugar, dizziness, nausea, and headache.

    Serious side effects — seek urgent medical care

    • Severe low blood sugar can cause confusion, seizures, or loss of consciousness. Seek urgent help for severe hypoglycaemia, jaundice, or a serious allergic reaction.

    Important interactions

    • Many medicines can alter blood glucose or the risk of hypoglycaemia with glimepiride — including some antibiotics, antifungals, beta blockers, corticosteroids, and other diabetes medicines. Ask your pharmacist to check for interactions.

    Allergy considerations

    • Avoid glimepiride if you have had a serious reaction to it or any product ingredient. Tell your doctor about relevant reactions to sulfonamide-related medicines.

    Pregnancy and lactation

    Pregnancy safety Generally avoided
    Notes
    • Glimepiride is generally not used during pregnancy. If you are pregnant, your diabetes treatment should be urgently reviewed by your obstetric and diabetes care team.

    Information

    Lactation safety Use with caution — see notes
    Notes
    • Discuss diabetes management while breastfeeding with a clinician — the plan for the infant and for your blood glucose control both need consideration.

    Children and older adults

    • Not intended for type 1 diabetes or children unless a specialist indicates otherwise. Older adults and people with kidney or liver problems have a higher risk of low blood sugar.

    Storage

    • Store in original packaging at room temperature as specified on the label. Keep away from children.

    Missed dose

    • Follow your prescription leaflet. Do not take an extra dose later to compensate. Ask your doctor about monitoring your glucose if you miss a dose.

    Overdose

    • An overdose can cause prolonged or recurring low blood sugar and requires urgent medical care — even if blood glucose improves after eating.

    This page is general information, not personal advice. Never change, start or stop any medicine without speaking to your doctor or pharmacist.