Pantoprazole

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    About this medicine

    Generic name Pantoprazole
    Active ingredients Pantoprazole (commonly supplied as pantoprazole sodium)
    Brand names (as verified) Pantocid; Protonix (brand availability varies by market)
    Dosage form Tablet
    Strength Common delayed-release tablet strengths include 20 mg and 40 mg; confirm product-specific instructions.
    Prescription classification Prescription only (Schedule H / verified)
    Approved routes of administration Oral
    Applies to IN; product status and availability may vary by jurisdiction

    Approved indications

    • A proton-pump inhibitor that lowers stomach acid. It is used for gastroesophageal reflux disease and selected acid-related conditions, including some cases of erosive esophagitis or excessive acid production.

    Contraindications (do not use if…)

    • Do not use after a serious hypersensitivity reaction to pantoprazole or another proton-pump inhibitor. Certain co-medications and formulations may be contraindicated; check the product label.

    Important precautions

    • Ongoing heartburn, difficulty swallowing, unexplained weight loss, blood in vomit or black stools need medical assessment. Long-term use may require review of magnesium, vitamin B12, bone and kidney concerns.

    Common side effects

    • Possible effects include headache, nausea, abdominal discomfort, gas, diarrhoea and joint pain.

    Serious side effects — seek urgent medical care

    • Seek medical care for severe persistent diarrhoea, serious allergic or skin reactions, reduced urine or symptoms of significant electrolyte disturbance.

    Important interactions

    • Review use with medicines such as warfarin, methotrexate, iron supplements and certain HIV medicines. A pharmacist should check all current medicines for clinically relevant interactions.

    Allergy considerations

    • Avoid after a serious reaction to pantoprazole or another proton-pump inhibitor. Review inactive ingredients when a formulation allergy is known.

    Pregnancy and lactation

    Pregnancy safety Use with caution — see notes
    Notes
    • Discuss use during pregnancy with a clinician, who can assess symptom severity, alternative options and the need for ongoing treatment.

    Information

    Lactation safety Use with caution — see notes
    Notes
    • Seek professional advice before prolonged use while breastfeeding, especially if the infant has medical concerns.

    Children and older adults

    • Approved ages and doses vary by formulation and indication. Persistent symptoms or long-term use in children require professional assessment.

    Storage

    • Store in original packaging at room temperature, away from excess heat and moisture. Keep away from children.

    Missed dose

    • Take a missed scheduled dose when remembered unless the next dose is near; do not double the next dose. Follow the prescription label.

    Overdose

    • Seek medical advice if an excessive amount is taken, particularly if symptoms develop or the amount is uncertain.

    Based on 1 cited source. Sources last checked on 2026-10-28.

    This page is general information, not personal advice. Never change, start or stop any medicine without speaking to your doctor or pharmacist.

    References

    1. openFDA Drug Datasets — openFDA Drug Datasets source (Regulatory / approved product label (e.g. CDSCO))
    2. RxNorm (NLM) — RxNorm (NLM) source (Regulatory / approved product label (e.g. CDSCO))