Amlodipine (commonly supplied as amlodipine besylate)
Brand names (as verified)
Amlong; Norvasc (brand availability varies by market)
Dosage form
Tablet
Strength
Common tablet strengths include 2.5 mg, 5 mg and 10 mg.
Prescription classification
Prescription only (Schedule H / verified)
Approved routes of administration
Oral
Applies to
IN; product status and availability may vary by jurisdiction
Approved indications
A calcium-channel blocker prescribed to manage high blood pressure and certain types of angina or coronary artery disease. Regular treatment can help control symptoms and reduce the risks associated with uncontrolled hypertension.
Contraindications (do not use if…)
Do not use after a serious hypersensitivity reaction to amlodipine or an ingredient in the product. Severe hypotension or particular cardiovascular conditions require clinician assessment.
Important precautions
May cause ankle or leg swelling, dizziness or low blood pressure. It controls some forms of chest pain but is not a rescue treatment for sudden chest pain. Do not stop prescribed treatment without medical advice.
Common side effects
Possible effects include ankle swelling, flushing, dizziness, tiredness, nausea and palpitations.
Serious side effects — seek urgent medical care
Seek urgent assessment for fainting, severe hypotension, a new or worsening chest-pain pattern, or a significant allergic reaction.
Important interactions
Certain CYP3A4 inhibitors and other blood-pressure-lowering medicines may affect its action. Amlodipine can raise exposure to simvastatin; the prescriber may need to limit or review that combination.
Allergy considerations
Avoid after a serious hypersensitivity reaction to amlodipine or any formulation ingredient.
Pregnancy and lactation
Pregnancy safety
Use with caution — see notes
Notes
Discuss treatment during pregnancy or when planning pregnancy with a clinician, who can review blood-pressure control and the most suitable medicine.
Information
Lactation safety
Use with caution — see notes
Notes
Seek professional advice about continued use while breastfeeding and whether monitoring is needed.
Children and older adults
Dosing and monitoring may differ for older adults and people with liver impairment. Paediatric use should follow specialist and product-specific guidance.
Storage
Keep in original packaging at room temperature and away from excess heat and moisture. Store securely away from children.
Missed dose
Take a missed dose when remembered unless close to the next scheduled dose; do not double up. Follow the patient-specific directions.
Overdose
An excessive amount can cause marked low blood pressure, dizziness, fainting or rapid heartbeat. Seek urgent medical help for suspected overdose.
If you suspect an overdose or accidental poisoning:
contact your local emergency services or the nearest hospital emergency department immediately. Do not wait for symptoms.
References
RxNorm (National Library of Medicine) — RxNorm (National Library of Medicine)source(Regulatory / approved product label (e.g. CDSCO))
Amlodipine (commonly supplied as amlodipine besylate)
Brand names (as verified)
Amlong; Norvasc (brand availability varies by market)
Dosage form
Tablet
Strength
Common tablet strengths include 2.5 mg, 5 mg and 10 mg.
Prescription classification
Prescription only (Schedule H / verified)
Approved routes of administration
Oral
Applies to
IN; product status and availability may vary by jurisdiction
Approved indications
A calcium-channel blocker prescribed to manage high blood pressure and certain types of angina or coronary artery disease. Regular treatment can help control symptoms and reduce the risks associated with uncontrolled hypertension.
Contraindications (do not use if…)
Do not use after a serious hypersensitivity reaction to amlodipine or an ingredient in the product. Severe hypotension or particular cardiovascular conditions require clinician assessment.
Important precautions
May cause ankle or leg swelling, dizziness or low blood pressure. It controls some forms of chest pain but is not a rescue treatment for sudden chest pain. Do not stop prescribed treatment without medical advice.
Common side effects
Possible effects include ankle swelling, flushing, dizziness, tiredness, nausea and palpitations.
Serious side effects — seek urgent medical care
Seek urgent assessment for fainting, severe hypotension, a new or worsening chest-pain pattern, or a significant allergic reaction.
Important interactions
Certain CYP3A4 inhibitors and other blood-pressure-lowering medicines may affect its action. Amlodipine can raise exposure to simvastatin; the prescriber may need to limit or review that combination.
Allergy considerations
Avoid after a serious hypersensitivity reaction to amlodipine or any formulation ingredient.
Pregnancy and lactation
Pregnancy safety
Use with caution — see notes
Notes
Discuss treatment during pregnancy or when planning pregnancy with a clinician, who can review blood-pressure control and the most suitable medicine.
Information
Lactation safety
Use with caution — see notes
Notes
Seek professional advice about continued use while breastfeeding and whether monitoring is needed.
Children and older adults
Dosing and monitoring may differ for older adults and people with liver impairment. Paediatric use should follow specialist and product-specific guidance.
Storage
Keep in original packaging at room temperature and away from excess heat and moisture. Store securely away from children.
Missed dose
Take a missed dose when remembered unless close to the next scheduled dose; do not double up. Follow the patient-specific directions.
Overdose
An excessive amount can cause marked low blood pressure, dizziness, fainting or rapid heartbeat. Seek urgent medical help for suspected overdose.
If you suspect an overdose or accidental poisoning:
contact your local emergency services or the nearest hospital emergency department immediately. Do not wait for symptoms.
References
RxNorm (National Library of Medicine) — RxNorm (National Library of Medicine)source(Regulatory / approved product label (e.g. CDSCO))
